Key Dates
Submission Deadline: June 15, 2025 (11:59 pm GMT)
Decision Announced: June 30, 2025
Call for Abstracts
The 6th International Symposium on Urea Cycle Disorders will include a poster session. Posters will be on display at the opening reception on Monday, September 1, the evening before the symposium, and during the symposium lunch session on Tuesday, September 2. We encourage all attendees working in the field of urea cycle disorders to share their work through this poster session. Predoctoral/postdoctoral trainees and junior faculty are especially encouraged to participate in the poster session as an opportunity to showcase their work. Selected abstracts will be available for viewing on the symposium website. Select submissions will receive a registration fee waiver for the 6th International Symposium on UCD.
Submissions
Please format your submission as shown below with the title capitalized, authors names, authors’ affiliations (Department, Institution, City, State/Province, Country). Organize the abstract under the following headings: Background, Methods, Results, and Conclusions. All abstracts must be submitted in English. Abstracts must not contain any graphics, tables, pictures, or other types of figures. The word limit for the body of the abstract is 400 words, excluding the title, authors, and affiliations. Please submit your abstract by 11:59 pm GMT on June 15, 2025.
Example:
HEALTH-RELATED QUALITY OF LIFE IN INDIVIDUALS WITH UREA CYCLE DISORDERS: A REPORT FROM THE UREA CYCLE DISORDERS CONSORTIUM
Natalie M. Gallant 1,2, Kara Simpson 3,7, Naghmeh Dorrani 1,2, Robert McCarter 3,4, Stephen D. Cederbaum 1,2,5, Ron D. Hays 6, and Uta Lichter-Konecki 3,7
1Department of Pediatrics, University of California Los Angeles, Los Angeles, CA, USA
2Department of Human Genetics, University of California Los Angeles, Los Angeles, CA, USA
3Center for Genetic Medicine and Center for Clinical and Community Research, Children’s National Medical Center, Washington, DC, USA
4Department of Pediatrics, George Washington University, Washington, DC, USA
5Department of Psychiatry, University of California Los Angeles, Los Angeles, CA, USA
6Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA
7Center for Neuroscience and Behavioral Medicine, Division of Genetics & Metabolism, Children’s National Medical Center, Washington, DC, USA
Background: Scant information is published on the impact of urea cycle disorders (UCD) on health-related quality of life (HRQOL). The aim of this study is to examine HRQOL in children and adults with UCD.
Methods: Estimates of HRQOL are based on data collected in the Longitudinal Study of the Urea Cycle Disorders Consortium. Children ages 5-17 without cognitive impairment and parents of all children ages 2-17 completed the PedsQL 4.0 survey. Adults ages 18 and older completed the SF-36v2 survey.
Results: 271 parents, 170 children and 217 adults with UCD participated. Parent-reported physical and psychosocial health scores were worse in children with neonatal-onset disease than late-onset disease. Both groups reported worse scores than healthy children. Children with neonatal-onset disease and their parents reported psychosocial health scores similar to children with cancer on chemotherapy. Adults with UCD, the majority of whom were asymptomatic, reported SF-36v2 physical and mental component summary scores similar to the general population.
Conclusions: Children with UCD have impaired physical and psychosocial health. Children with neonatal-onset UCD have psychosocial health similar to children with cancer on chemotherapy. Further studies are needed to identify mechanisms that might ameliorate the negative impacts of UCD on HRQOL.
Abstract Review and Selection
Abstracts will be reviewed by a panel of experts and authors will be informed of acceptance by June 30, 2025. Selected posters will be presented at the poster sessions at the 6th International Symposium on UCD. Top selections will receive a registration fee waiver and may be featured on the symposium website and may be published in the special issue of Molecular Genetics and Metabolism.
Abstract Publication
Select abstracts may be made available on the symposium website. As this is a public website, the abstract and all information will become a matter of public record. Select abstracts may be published in Molecular Genetics and Metabolism, the official journal of the Society for Inherited Metabolic Disorders. If you would like to opt out of publication on the meeting website or in Molecular Genetics and Metabolism, please contact symposium organizers.
If you prefer not to have your abstract published, indicate that you are opting out on the abstract submission form.
Poster Specifications for Selected Abstracts
The posters need not be distinct from those to be displayed at the ICIEM that follows the symposium. The poster specifications are the same as for the ICIEM submissions.
